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diagnosis differential management hyperthermia nephrology toxicology toxidromes anesthesia anesthesiology checklist classification elevation hyperthermic hypnotics hypokalemia lactate lactic opioids perioperative rhabdomyolysis
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
toxidrome is a syndrome ... set of symptoms) caused ... hydromorphone, etc ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... TNF-a1pha, IL-6, etc ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... Actively maintained fever ... CAUSES OF HYPERTHERMIA ... sign) (→ 3-8) • Serotonin ... phencyclidine, MDMA) • Anticholinergic
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... hypoxemia/Sepsis etc ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... Renal tubular acidosis ... , Heat stroke, Fever ... #Hypokalemia #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Herpes, Coxsackie, etc ... Muscle swelling - Fever ... per day until stable ... Diagnosis #Management #causes
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
• Anticholinergic ... • Serotonin Syndrome ... pharmacogenetic disease caused ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis
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