11 results
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia

- BWH Medicine Chiefs @BrighamChiefs

#Serotonin #Syndrome #Neuroleptic
Comparison - Serotonin ... BrighamChiefs #Serotonin ... Catatonia #NMS #SS #comparison ... #diagnosis #management ... #treatment #table
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... set of symptoms) caused ... hydromorphone, etc ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... sign) (→ 3-8) • Serotonin ... syndrome (cocaine ... phencyclidine, MDMA) • Anticholinergic ... Checklist #Diagnosis #Management
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Herpes, Coxsackie etc ... per day until stable ... #Summary #causes ... #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Herpes, Coxsackie, etc ... per day until stable ... #causes #treatment
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Torsades de Pointes - Management ... Syndrome Electrolyte ... Hypocalcemia (rarely) Treatment ... 1b (lidocaine)- case ... TorsadesdePointes #TDP #Management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... Treatment: • ... SPS #Diagnosis #Management ... #treatment #neurology
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
Anticholinergic ... • Serotonin Syndrome ... pharmacogenetic disease caused ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... Rheumatology #diagnosis #management