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diagnosis toxicology toxidromes differential hyperthermia management sympathomimetics anesthesia anesthesiology checklist fever hyperthermic hypnotics perioperative sedatives workup
Signs and Symptoms of Toxidromes Sympathomimetic / GABAergic withdrawal Cholinergic Anticholinergic Opioid withdrawal Neuroleptic malignant syndrome Serotonin
Opioid withdrawal ... Serotonin syndrome ... #Toxidromes #Comparison ... #Table #Anticholinergics ... #Opioids #Sympathomimetics
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
toxidrome is a syndrome ... set of symptoms) caused ... hydromorphone, etc ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Toxidromes Summary Table Heart Rate - Respiratory Rate - Blood Pressure - Mental Status - Skin -
Toxidromes Summary Table ... - Reflexes • Opioid ... Sympathomimetic • Anticholinergic ... • Serotonin Syndrome ... #Toxidromes #comparison
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... sign) (→ 3-8) • Serotonin ... syndrome (cocaine ... phencyclidine, MDMA) • Anticholinergic ... #Differential #Causes
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment: ... #Hyperthermia #comparison
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
• Anticholinergic ... • Serotonin Syndrome ... pharmacogenetic disease caused ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis
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