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A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... set of symptoms) caused ... hydromorphone, etc ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Hyperthyroidism, Serotonin ... syndrome, Eclampsia ... differential #diagnosis #table ... #neurology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... sign) (→ 3-8) • Serotonin ... phencyclidine, MDMA) • Anticholinergic ... Phaeochromocytoma Neurologic
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment: ... #Hyperthermia #comparison
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... Caused commonly ... Treatment: anticholinergics ... FatimahDandan #Pisa #Syndrome ... PhysicalExam #clinical #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... autoantibodies - TPO, TTG, etc ... Treatment: • ... Diagnosis #Management #treatment ... #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Herpes, Coxsackie, etc ... per day until stable ... Diagnosis #Management #causes ... #treatment #nephrology
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
Anticholinergic ... • Serotonin Syndrome ... pharmacogenetic disease caused ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis