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Serotonin Syndrome Differential Diagnosis: Anticholinergic syndrome, Neuroleptic malignant syndrome, Malignant hyperthermia  #Diagnosis #Differential #Serotonin #Syndrome
Serotonin Syndrome ... Differential Diagnosis: Anticholinergic ... , Malignant hyperthermia ... MalignantHyperthermia #Comparison ... #Table #Differential
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Peri-operative Hyperthermia ... Treatment depends ... sign) (→ 3-8) • Serotonin ... phencyclidine, MDMA) • Anticholinergic ... Phaeochromocytoma Neurologic
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment: ... #comparison #diagnosis
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
Anticholinergic ... • Serotonin Syndrome ... dopamine blockers (e.g ... #Toxidromes #comparison ... #table #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Exertional: - Hyperthermia ... - Malignant hyperthermia ... Herpes, Coxsackie, etc ... per day until stable ... #nephrology