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management neurology syndrome differential physicalexam algorithm cardiology criticalcare guillain hemophagocytic hlh lymphohistiocytosis symptoms video 21hydroxylasedeficiency 21ohd adhesivecapsulitis amyotrophic anesthesia anesthesiology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Motor Nerves: ALS ... Poliomyelitis, Guillain-Barre ... #differential #diagnosis
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Pathophysiology ... Clinical Features ... Diagnosis: • ... #Syndrome #diagnosis
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... the underlying pathophysiology ... and cauda equina TREATMENT ... intensive care unit (ICU
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... #Meningitis #Clinical ... #PhysicalExam #Pediatrics ... #Peds
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 21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... Signs/Symptoms/Complications ... endocrinology #peds ... #pediatrics
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Generalized fatigue - ALS ... myasthenia Diagnosis ... Bedside: ice pack ... test - Cogan sign ... - Peek sign
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
such as reflex ... orthostatic vital sign ... and an initial ECG ... should be guided by clinical ... The treatment strategy
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
pancreatitis but can also ... conditions that cause ... Pathophysiology: ... pregnancy, or other causes ... peritonitis #IM #FM #ICU
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
organ dysfunction caused ... Clinical construct ... likelihood of prolonged ICU ... recognition and treatment ... #criticalcare #icu
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Drugs, Unknown cause ... Treatment: • ... of emergency, ICU
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