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diagnosis symptoms erythematosus lupus pain sle systemic approach management vasculitis workup arteritis autoantibodies autoimmune behcet classification clinical gap gca giantcell
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... Inflammatory, crystalline disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... necrosis, and Paget disease ... #Pain #MSK #rheumatology ... approach #workup #differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
) - MSK Radiology ... mass and NO prior signs ... Differential diagnosis ... diffuse chondral disease ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... - Hemolytic anemia ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... Musculoskeletal: Joint ... Hematological: Anemia ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
aseptic meningitis), MCC ... : Arterial (MCC-small ... ) Differential Diagnosis ... diagnosis #management #signs ... #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... : • Joint pain ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
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