21 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... (DILI) Viral Hepatitis ... #Hepatology #gastroenterology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
of Cirrhosis ... ascites removed • Acute ... • Hepatorenal syndrome ... #Cirrhosis #treatment ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... or fibrosis • Cirrhosis ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Clues to non-cirrhotic ... • Budd Chiari syndrome ... /acute hepatitis ... Diagnosis #causes #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... Diagnosis and Management ... viremia or have cirrhosis ... Algorithm #Diagnosis #Management ... #Treatment #Hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... disease - Cirrhosis ... - Alcoholic hepatitis ... fibrosis - Acute ... #differential #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... : < 1 • Cirrhosis ... • Gilbert's syndrome ... #differential #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... (eg Viral) Management ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
vein: Budd-chiari syndrome ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology