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diagnosis differential rheumatology causes management nephrology secondary acidosis activation algorithm arthritis cardiology crisis cryoglobulinemia cryoglobulins dermatology disease elevation endocarditis erythematosus
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
Causes of Acute ... Cardiac injury (e.g ... Pericardial perforation (e.g ... pericarditis) Uremia ... Systemic lupus
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 SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... : • Acute cutaneous ... • Malignancy (e.g ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... tissue disorder (e.g ... . systemic lupus ... diagnosis #types #classification ... #rheumatology #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... of Circulatory System ... - Compartment syndrome ... 30mmHg) - Severe anemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... the presence of anemia ... Screening Tests for Acute ... inflammatory disease (e.g ... Chemistry profile (e.g
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Renal Crisis: 1) Acute ... microangiopathic hemolytic anemia ... other pathology (e.g ... (short-acting, e.g ... vasodilators (ERAs
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Culture Positive: • Acute ... Vascular: • Systemic ... Cholesterol emboli syndrome ... ↑ ESR, CRP • EKG ... Leukocytosis, anemia
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