15 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
and Workup Step ... volume loss - diuretics ... liver failure • nephrotic ... syndrome • renal ... #Algorithm #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... • Euvolemic (Low ... , Cushing syndrome ... #Algorithm #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
failure, Cirrhosis, Nephrotic ... syndrome - ... , Medications (diuretics ... Primary polydipsia, Low ... #sodium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Renal losses, Diuretic ... UNa > 20: • Acute ... , UNa < 20 • Nephrotic ... #Causes #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Syndrome of Inappropriate ... especially thiazide diuretics ... Cirrhosis • Nephrotic ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Syndrome of Inappropriate ... especially thiazide diuretics ... Cirrhosis • Nephrotic ... #Nephrology #Differential
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Diagnosis Algorithm ... Beer Potomania - Low ... liver failure, nephrotic ... syndrome ... #causes #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... failure, Cirrhosis, Nephrotic ... syndrome) • ADH ... table #sodium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute ... kidney disease, and nephrotic ... syndromeHyponatremia ... kidney disease, and nephrotic ... #Nephrology #Pharmacology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Hypothyroidism, Low ... failure, Cirrhosis, Nephrotic ... syndrome • Urine ... #algorithm #diagnosis ... #sodium #low #nephrology