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differential erythematosus management signs symptoms ana antibodies antinuclear classification disease hematology pain patterns syndrome vasculitis activation associations autoantibodies autoimmune bone
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... (SLE), Systemic ... #rheumatology # ... diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... • Pulmonary ... • Shrinking lung ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(SLE), Systemic ... (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology # ... diagnosis #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... effusion, Restrictive lung ... of hip (rare), Arthritis ... #SLE #systemic ... #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
disease-associated interstitial lung ... RA: rheumatoid arthritis ... SLE : systemic ... lupus. ... #Rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... : - Arthritis ... Myositis 4% - Lung ... #Systemic #Lupus ... #differential #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... in at least 2 joints ... #Systemic #Lupus ... Erythematosus #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... : • Joint pain ... #Systemic #Lupus ... #Rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... dz difficult to see ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... lupus erythematosus ... - (C-ANCA) pattern ... vasculitis, and SLE ... #rheumatology #
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