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differential disease pain rheumatoid signs symptoms syndrome testing apml bone calcium causes conditions cppd deposition differentiation extrarticular fungal infections infectiousdiseases
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... • Interstitial lung ... • Shrinking lung ... #differential #diagnosis ... #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... titer, ACE level, CXR ... #laboratory #workup ... #diagnosis #testing ... #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
5 or elevated Cr ... common • Imaging: CXR ... - pulmonary opacities ... sepsis), PE, DAH, CHF ... #management #hematology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Musculoskeletal: Joint ... Signs #Symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... vesicular eruption • Joints ... Cerebrospinal fluid (CSF ... Palpable purpura, joint ... #Rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
swelling in weird joints ... culture used to diagnose ... ≥2 attacks • Long-term ... Deposition #Disease #Rheumatology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... Arthralgia and Arthritis ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... muscle aches, joint ... change in the lungs ... Meningitis, septic arthritis ... #Management #Infections
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