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differential hematology oncology management algorithm cd4 conditions differentiation evaluation extrarticular fungal hivaids hypertension infectiousdiseases leukemia mds mycoses myelodysplasia myelodysplastic pain
Diagnostic algorithm for a child or adolescent with suspected pulmonary hypertension. CHD, congenital heart disease; CPET,
Diagnostic algorithm ... CHD, congenital ... hypertension; CXR ... ; CLD, chronic lung ... #Hypertension #Workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
common • Imaging: CXR ... - pulmonary opacities ... : Infection (sepsis ... ), PE, DAH, CHF, ... #hematology #oncology
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... failure, COPD, Lung ... • CD4 < 200: Pulmonary ... Evaluation: Imaging (CXR ... #workup #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... manifestations, hypoxia, CXR ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... • Interstitial lung ... • Shrinking lung ... #differential #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... vesicular eruption • Joints ... Cerebrospinal fluid (CSF ... Palpable purpura, joint ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... petechiae) • Frequent infections ... • Parvovirus infection ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... muscle aches, joint ... MC: CNS CSF: • ... change in the lungs ... nails, bronchi, lungs
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