22 results
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... of GHB toxicity ... Hydroxybutyrate #GHB #Toxicology ... #Toxicity #Diagnosis ... #Management #Pharmacology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... ingestion/exposure Symptoms ... Salicylate #Aspirin #Toxicity ... #Toxicology #diagnosis
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... post-ingestion) - Symptom ... absent in severe toxicity ... #Toxicology #Diagnosis ... #Management #Ferrous
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
hypothalamic tumors and ectopic ... Carpal Tunnel Syndrome ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
anaerobic metabolism Diagnosis ... also includes symptoms ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis ... #Management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... Atorvastatin Diagnosis ... Statin #muscle #toxicity ... #myopathy #diagnosis ... #management #treatment
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
and Management ... Diagnosis - Caine ... treatment can improve symptoms ... development of Korsakoff syndrome ... #Management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Neurological symptoms ... Medication/Drug toxicity ... #diagnosis #management ... #neurology
Histamine Fish Toxicity - Inadequate refrigeration increases enzyme from bacteria on fish 
Clinical 
• Skin flushing,
Histamine Fish Toxicity ... palpitations • Symptoms ... eating fish Management ... Histamine #Fish #Toxicity ... #Toxicology #Diagnosis
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
respiratory distress syndrome ... gradually with symptoms ... pneumonitis Diagnosis ... Improvement in symptoms ... #management #Toxicology