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diagnosis management rheumatology anticoagulation antiphospholipid aps encephalopathy erythematosus guidelines hematology lupus macrophage mas neurology posterior pres reversible sjogrens sle systemic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Clinical Presentation ... lymphadenopathy • Central ... nervous system ... Treatment: • Corticosteroids
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... form in arteries, veins ... at least: • 1 clinical ... to be present Treatment ... (EULAR Guidelines
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
brain PRES Clinical ... CSF: Modestly elevated ... An elevated white ... epilepticus Treatment ... underlying cause • Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Clinical Features ... sediment, and elevated ... serum creatinine ... Chronic B-cell activation
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... gland) biopsy • Ocular ... salivary ducts Clinical ... Involvement: • Central ... Adenocarcinoma Treatment
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