15 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... Like in this case ... #Joint #Pain #MSK ... rheumatology #approach #workup
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
disease Inflammatory ... Joint Disease ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... disease must be ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... prematurely • risk of joint ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... - Pain (muscle/joint
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... value is low, tests ... indirect antiglobulin tests ... Mild-to-moderate elevation ... #Workup #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... presentations and disease ... tests before beginning ... Join the resistance ... #typeb #classification
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... a stroke that caused ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... stages #staging #msk
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Some sort of end point ... #PCL #Injury #MSK ... #Sports #pathophysiology ... #classification ... #diagnosis
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
you’ll do a good workup ... can drive this disease ... As with many disease ... Best to have an ... #Algorithm #workup
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... negative, MOG-IgG test ... • Infectious causes ... MCTD - Bechet disease