14 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
• Urogenital Lesions ... ) • Cutaneous Lesions ... 75%): acneiform lesions ... #diagnosis #management ... signs #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... Cranial nerve lesions ... Demyelinating syndromes ... , Aortic valve lesions ... symptoms #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... Discoid skin lesions ... differential #diagnosis #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
skin and mucosal lesions ... bluish-red bumps or lesions ... solid, raised lesions ... can precede skin lesions ... #dermatology #oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
vasculitis Skin lesions ... • Painful skin lesions ... Papulo-necrotic lesions ... reticularis • Necrotic lesions ... gangrene Skin lesions
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... for refractory lesions ... or refractory lesions ... #Treatment #management ... #pharmacology #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
LLN B - Bony lesions ... 100 • >1 focal lesions ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... : - Genetic lesions ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... Photosensitive rash ... papulosquamous lesions ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
ischemic skin lesions ... , mucositis • Rash ... Vasculitis: • Skin lesions ... maculopapular lesions ... Ocular inflammatory lesions