12 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Palpable purpura, Hemorrhagic ... IgM deposits • Nodular ... cutaneous vasculitis ... #Vasculitis #skin ... #dermatology #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... rash (6.7%) • Hemorrhagic ... (inflamed blood ... Polyangiitis #GPA #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
aphthous ulcers, cutaneous ... , ocular, articular ... strong sign of cutaneous ... pulses, bruis, or blood ... Large Vessel: Blood
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
drug injections, renal ... steroid use Dx: skin ... hyphae invading blood ... #dermatology #skin ... #clinical #photo
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... vasculitis) • ... Cutaneous Lesions ... Behcet syndrome (Clinical ... signs #symptoms #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
than 2 mm) of hemorrhage ... : • Complete blood ... cryoglobulins • Skin ... • Abdominal ultrasound ... Algorithm #Causes #dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... Strong sign of cutaneous ... pulses, bruits, or blood ... , ocular, articular ... Cogan syndrome: Ocular
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... thrombosis+Pulm HTN+skin ... , retinal, DVT, ... Paraproteinemias #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... malignancies, vasculitis ... pulmonary emboli, and ocular ... thrombi including retinal ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Erythematous, macular ... Malignancy (e.g. hematologic ... Diffuse alveolar hemorrhage