13 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + DPP4 ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Management #Diabetes #DM2 ... #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Receptor Agonists • DPP4i ... #Medications #pharmacology ... #pathophysiology ... #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... Diabetes #Mellitus #DM2 ... #Medications #pharmacology ... comparison #table #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
: Weight-Based Dosing ... #TDD #Insulin #dosing ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... oral route by using ... empagliflozin and DPP4 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly: frontal bossing ... malignancy Pathophysiology ... Pegvisomant) ± D2 ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... days prior to chemotherapy ... Dosing: 100 mg ... /m2/dose every 8 ... #pathophysiology