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hodgkins lymphoma algorithm anemia biliary causes chronic cirrhosis classification cll dermatology gap globulin hemolytic leukemia lymphocytic management mds myelodysplasia myelodysplastic
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... procedures - Infection ... #Platelet #Disorders ... #Workup #hematology
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders ... • Production: Liver ... Spleen-mediated - Infection-mediated ... #Disorders #Differential ... #Diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
SLE) - Viral infections ... deficiency • Liver ... APLS • Acute Infectious ... #Diagnosis #hematology ... #rheumatology #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
with or without platelet ... Schistocytes, thrombocytopenia ... inclusions - If infection ... Consider RBC membrane disorder ... #workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
PBC Signs and Symptoms ... malignancies, Hepatic ... fungal, viral infections ... #diagnosis #workup ... #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... Etiology: - Infections ... Diagnosis of B-Symptoms ... #oncology #diagnosis ... hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... petechiae) • Frequent infections ... • Parvovirus infection ... blood count with differential ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... lymphoproliferative disorders ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Include: • Viral infections ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... #diagnosis #hematology
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