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hematology chronic lymphocytic lymphoma management causes classification dehydrogenase elevated erythematosus gap globulin hemeonc hemolytic laboratory lactate ldh lupus mds myelodysplasia
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... involved) • No leukemic ... Etiology: - Infections ... Diagnosis of B-Symptoms ... #oncology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
in adults • Disorder ... Complications: 1) Infection ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... ingestion • B symptoms ... Lymphoma Workup ... #oncology #management
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... inclusions - If infection ... Consider RBC membrane disorder ... Diagnosis #Algorithm ... #workup #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... pylori test (GI symptoms ... changes), high MCV anemia ... #Workup #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
paralyses CNS Disorders ... • Toxins • Infection ... Lymphomas • Leukemias ... Polyarteritis nodosa • Eosinophilic ... associated with any symptoms
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... petechiae) • Frequent infections ... Myeloproliferative Disease ... • Parvovirus infection ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia
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