7 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PURPURA: Vasculitis ... /HSP • Cryoglobulinemia ... Associated - SLE, Sjogren's ... #hematology #rheumatology ... #nonpalpable #dermatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... Labs/Diagnosis: ... syndrome) #Cryoglobulinemia
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Mixed cryoglobulinemia ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Collagen disorders ... (lupus, RA, Sjogren's ... #Algorithm #Causes ... #dermatology #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... affects the skin, neurologic ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... : • 7%, Cryoglobulinemia ... #Syndrome #Rheumatology ... #Diagnosis #Management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... Associated Disorders ... Skin necrosis • Purpura ... Antiphospholipid syndrome ... hematology