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diagnosis differential management algorithm oncology rash classification clinical cryofibrinogenemia cryoglobulinemia cryoglobulins cutaneous dermatologic discoloration eosinophil eosinophilia fingernails flecainide globulin gpa
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... vasculitis - GPA ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... vasculitis #Dermatologic ... #dermatology #rash ... #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... eosinophilia (common causes ... symptoms (eg, skin ... Differential #diagnosis #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... reticularis & skin ... classification #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Vasculitis - Collagen disorders ... RA, Sjogren's, GPA ... cryoglobulins • Skin ... #dermatology #physicalexam
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... gammopathy, and skin ... Connective tissue disorders ... gastric tumors • Hematology ... differential #diagnosis #hematology
If you haven't seen it, flecainide can cause significant yellowing of the skin and eyes.
flecainide can cause ... yellowing of the skin ... In this case just ... #photo #nails #cardiology ... #dermatology #discoloration
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... CLL -> Invade Skin ... #Leukemia #Hematology
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