Erythematous Rash Differential neurology clinical systemic classification arthritis vasculitis algorithm cryoglobulinemia sle syndrome antinuclear gpa types

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Cryoglobulinemia Summary

Cryoglobulins:
• Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below

Syndrome: • Clinical ... - type II cryoglobulinemia ... lupus erythematosus ... syndrome) #Cryoglobulinemia ... #classification

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

mucositis - Rash ... lupus erythematosus ... • ANCA (Dx: GPA ... , and SLE) • Urinalysis ... #rheumatology #classification

Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and

Rarely dominate the clinical ... reticularis Differential ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... • Giant cell arteritis

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... Skin Disease Classification ... rash • Erythematous ... permanent alopecia Differential ... Kikuchi disease • Type-I

Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,

Vasculitis - Differential ... diseases, such as SLE ... ischemia • Skin: Erythematous ... , mucositis • Rash ... / ANCA + MPO) Cryoglobulinemic

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... 7%, Cryoglobulinemia ... Arthralgia and Arthritis

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