11 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
clinically significant ... , Sjögren Syndrome ... , Myositis, Mixed ... Drug-Induced, Inflammatory ... rheumatology #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... photosensitivity, inflammatory ... Classification: ... permanent alopecia Differential ... • Transverse Myelitis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... aneurysms can also ... disease Differential ... , such as systemic ... purpura: strong sign
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... (25-75%): Inflammatory ... matter, spinal cord ... Medium and large also ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... ischemia • Skin: Erythematous ... , mucositis • Rash ... : Ocular inflammatory
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- Clinical Presentation ... • Bilateral signs ... - Sjogren - Vasculitis ... #diagnosis #management ... #neurology #differential
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... , neurologic, and ... Diagnosis = clinical ... very remarkable w/differential ... Symptoms #Diagnosis #Management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... double-stranded DNA antibodies ... level to exclude myositis ... ANA and RF (if clinical
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... central nervous system ... • Inflammatory ... neuritis • Partial myelitis ... • Or brainstem syndromes
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the nervous system ... can become pro-inflammatory ... multiple spinal cord ... Lateral #Sclerosis #neurology ... #diagnosis #management