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Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Framework PRE-Renal ... AKI: • Hypovolemia ... Shunting INTRA-Renal ... Drug-induced POST-Renal ... Differential #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Framework Pre-Renal ... : • Hypovolemia ... Hypercalcemia, Renal ... Medications Intra-Renal ... Autoimmune Post-Renal
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
K+: • Tissue injury ... glycosides • High ... Decreased K+ Elimination ... : • AKIHypovolemia ... blockers - MCW Nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
renal potassium ... excretion • Acute renal ... failure • Chronic renal ... : • Post-renal ... #nephrology #potassium
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
to Acute Kidney Injury ... protein/Cr - Renal ... - 45% - Pre-renal ... mostly ATN and pre-renal ... #Algorithm #Causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Diagnosis Algorithm ... Extra-renal Losses ... loss (Diarrhea) Renal ... Syndrome • HTN, High ... potassium #low #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
- AKI Workup Algorithm ... urinary sediment, renal ... HIV serology, renal ... eosinophiluria, renal ... #AKI #Workup #Algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
HYPOTENSION → renal ... vasoconstriction → decreased renal ... perfusion → renal ... Cast formation: Renal ... causes #treatment #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
of Acute Kidney Injury ... Diagnosis Algorithm ... at least 50% Renal ... Sjögren) Post-Renal ... #KidneyInjury #Nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... ≥100): SIADH, Renal ... diuresis can be high ... Present (Uosm <100): Renal ... Hypervolemia with poor renal