23 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Liver Function Tests ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
increased B-cell activity ... renal failure Clinical ... are not caused ... anterior/posterior MSK ... : (distinct symptoms
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... and petechiae Causes ... • Improve the symptoms ... #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... skin that are caused ... Marrow Failure • Chronic ... #diagnosis #hematology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
decrease in the active ... Chronic abuse of ... a syndrome identical ... The classic clinical ... of pernicious anemia
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... adults in the west ... Orange or Hep C Clinical ... with no early symptoms ... • Neutropenia, anemia
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... inhibition - Chronic
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... sensing) vs tumor vs exogenous ... normal/high - Chronic ... about secondary causes ... Best to have an