18 results
diagnosis management oncology rheumatology anemia differential hemophagocytic hepatology hlh leukemia lymphohistiocytosis signs treatment workup agglutinin algorithm aplastic bilirubin bleeding bruising
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
increased B-cell activity ... renal failure Clinical ... are not caused ... anterior/posterior MSK ... : (distinct symptoms
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
• Has a UGT1A1 activity ... as jaundice on clinical ... examination; nonspecific symptoms ... and stress may cause ... Congenital #bilirubin #hepatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... sensing) vs tumor vs exogenous ... about secondary causes ... Best to have an ... Algorithm #workup #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... Rule out other causes ... blockers had the best ... diagnosis #management #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... HLH signs and symptoms ... absent NK cell activity ... management #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... and petechiae Causes ... • Improve the symptoms ... Anemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Diagnosis and Clinical ... , oral cavity) Caused ... dexamethasone suppression test ... Diagnosis #signs #symptoms
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
cascade is intact - test ... von Willebrand syndrome ... discern these causes ... liver function tests ... Differential #Diagnosis #Hematology
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