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diagnosis management hematology oncology leukemia differential infections infectiousdiseases lymphocytic neurology syndrome classification cns comparison druginduced encephalopathy fungal hemeonc hemophagocytic hiv
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... Tyrosine Kinase activity ... -> AML: Blast crises ... ) CLL Symptoms:
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... with no early symptoms ... cells can indicate disease ... microglobulin Treatment
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... immunophenotype Clinical ... chemotherapy for low-risk disease ... #Chronic #Lymphocytic
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
contagious of all ... The signs and symptoms ... resembling rashes caused ... Rash #Diagnosis #Clinical ... #Photo #Dermatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Infection in HIV / AIDS ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease ... caused by the JC
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... • Treatment: ... • Evolution: Chronic ... disease Dr.
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... HLH signs and symptoms ... activity • Ferritin ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Syndromes #diagnosis #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... Neurological symptoms ... the underlying cause ... • Treatment of ... until cause identified
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
of HIV/AIDS patients ... worsening of that disease ... be present: • AIDS ... initiation Clinical ... • Persistently active
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