18 results
Sweet’s Syndrome - Acute febrile neutrophilic dermatosis 

The syndrome involves fever, painful rash, neutrophilic leukocytosis, and
febrile neutrophilic dermatosis ... fever, painful rash ... #neutrophilic #dermatosis ... #dermatology #Rash ... #Skin #Clinical
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
based on repeat clinic ... • Nephritic syndrome ... • Bilateral RAS ... Steroids (Cushing's, exogenous ... • Unilateral RAS
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Neutrophilic dermatoses ... - Rash: multiple ... Causes: - Idiopathic ... #diagnosis #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... • Goodpasture syndrome ... #rash #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... purpura to mucosal bleeding ... Petechial or purpuric rash ... Diagnosis #Management #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... immune system, leading ... • They can cause ... Cryoglobulins Cause ... : • Clinical triad
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Willebrand factor activity ... ristocetin cofactor activity ... von Willebrand syndrome ... discern these causes ... Differential #Diagnosis #Hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... and neutrophilic dermatoses ... Diagnosis: • A clinical ... Rule out other causes ... diagnosis #management #Dermatology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... by N2O, leading ... decrease in the active ... a syndrome identical ... The classic clinical