338 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Pathophysiology EXOGENOUS ... components Exogenous ... , IFN, IL-6 ENDOGENOUS ... vasculature via: • Active ... organs CNS - Endogenous
Headache Differential - Primary vs Secondary
A vast number of diseases can cause a headache. We divide
of diseases can cause ... headaches are caused ... by various exogenous ... Primary #Secondary #Table
Staging of Skin Mottling

Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... endogenous vasoconstriction ... not additional exogenous
Hyperthyroidism and Thyrotoxicosis Interpretation Table
 - Autonomy (Graves)
 - Autonomy (toxic nodule)
 - Exogenous thyroid hormone
Interpretation Table ... toxic nodule) - Exogenous ... Interpretation #Table
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: → Exogenous ... pro-inflammatroy mediators (Endogenous ... Pyrogen) → Endogenous ... vasculature via: • Active ... circumventricular organs CNS: Endogenous
Systemic Glucocorticoid Dose Equivalents. 

Note: approximate equivalent dose is based on anti-inflammatory potency. Fludrocortisone is not
mineralocorticoid activity ... anti-inflammatory activity ... chemotherapy induced nausea ... (postoperative nausea ... Steroid #Conversion #Table
Polyuria - Differential Diagnosis
Solute Diuresis
 • Na intake/saline
 • Glucosuria: Hyperglycemia, SGLT-2 inhibitors
 • Urea: Exogenous
inhibitors • Urea: Exogenous ... Differential #Diagnosis #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... Pseudo-hyperaldosteronism: exogenous ... diagnosis #algorithm #causes
Hyperaldosteronism - Etiologies of Mineralocorticoid Excess

Primary Hyperaldosteronism (Normal or Low Renin, High Aldosterone) 
 - Aldosterone-secreting
syndrome - Exogenous ... Aldosterone #Comparison #Table
Amenorrhea - Differential Diagnosis Algorithm
Elevated FSH
 • Premature Ovarian Failure
 • Menopa use
 • Spontaneous
Bleed With
Diabetes Mellitus • Exogenous ... Hyperprolactinemia Organic Cause ... endocrinology #causes