16 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : • Pauci-Immune ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... the underlying pathophysiology ... Guillain #Barre #Syndrome ... #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... (GBS), systemic ... Atorvastatin Diagnosis ... IU/I • SAMS clinical ... increased spontaneous activity
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... present Ag to CD4 ... activate complement ... amplitude of secondary immune ... Humoral #Immunity #pathophysiology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... - Differential Diagnosis ... should be based on clinical ... required until immune ... #AIDS #opportunistic
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... Guillain-Barre Clinical ... #treatment #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... initiation Clinical ... • Persistently active
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... Tuberculosis Diagnosis
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
urinary catheter and immune ... compromise Clinical ... Pathophysiology: ... lactulose producing gas ... pyelonephritis CMC
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... may precede the neurologic ... Etiology: • Pathophysiology ... Seizures: Treat with AEDs ... #neurology