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diagnosis differential management associated barre dementia guillain guillainbarre hand hematology hemeonc hemophagocytic hlh infections infectiousdiseases inflammatory iris lymphohistiocytosis myelitis neurocognitive
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... should be based on clinical ... required until immune ... Suspect in movement disorders ... differential #diagnosis #AIDS
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... and infects the CNS ... syndrome of HAD ... #dementia #AIDS ... #Neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... Lack of UMN/LMN signs ... • Inflammatory disorders ... Polymyositis • Immune ... parainfluenza, Coxsackie, HIV
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... Campylobacter jejuni - HIV ... management #treatment #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... initiation Clinical ... pleural effusions, CNS
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Transverse Myelitis - Clinical ... • Bilateral signs ... simplex virus, HIV
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... asymmetric arm BP ... affects the skin, neurologic ... cognitive impairment, neurologic ... chorioretinitis, CNS
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Clinical Presentation ... • Common Signs ... Pathophysiology ... of NK cells and CD8 ... malignancy, autoimmune disorder
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