39 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... exposure to allergen causes ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... cells can indicate disease ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... #Summary
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver disease ... Multiple myeloma, CML ... - Significant endogenous ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... Cytopenia: Common • Immunologic ... Positive in 60-80% of cases ... Evolution: Chronic disease
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... Summary Clinical ... demineralization) • Renal disease ... plasma clonal cell ... is also >100 CMC
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Renal Cell Carcinoma ... Summary Clinical ... Budd Chiari syndrome ... Hb levels and CBC ... #Summary
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... epidemiology of this disease ... history of the disease ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology