11 results
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... viremia or have cirrhosis ... , HIV, HCV. ... HAV immunity; Liver ... #Treatment #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
, HBV, HCV, HEV, ... Benign/malignant biliary ... obstruction, Primary biliary ... e.g. ascites), Chronic ... Diagnosis #Algorithm #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
HIV/HCV co-infection ... family history of HCC ... mg/dL) or acute liver ... #Indications #management ... #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Differential Diagnosis Chronic ... liver disease ( ... cirrhosis or chronic ... Failure, Pancreatic, Biliary ... Differential #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... #ACLF #Acute #Chronic ... #Cirrhosis #Hepatology ... #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
, HBV, HCV, HEV, ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... injury: > 3 • Chronic ... diagnosis #algorithm #hepatology
Hepatitis B Disease Progression Timeline
 • > 90% of infected children progress to chronic disease (<5%
develop Liver Cancer ... (HCC) • 20-30% ... of chronic HBV-infected ... of developing cirrhosis ... Timeline #Prognosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis serologies, HCV ... hepatitis serologies, HCV ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
PSC) PSC is a chronic ... to multi-focal biliary ... colorectal and hepato-biliary ... disease management ... #summary #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Patients with cirrhosis ... been ruled out, HIC ... with elevated HIC ... algorithm #diagnosis #management ... #hepatology #gastroenterology