9 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... immune deficiency, Drugs ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Epigastric abdominal pain (90%, characteristically
and Management ... surgery, Trauma, Drugs ... PUD (posterior), Anatomic ... dysfunction), Familial, Infectious ... #Management #Treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... Idiopathic • Infections ... aplastic anemia Treatment ... #diagnosis #management
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
contralateral eye ... intraocular levels of drug ... #management #opportunistic ... #infections #HIVAIDS ... #pharmacology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SLE], AOSD) • Infection ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... concomitant infection ... comorbidities/drug ... #management #treatment ... #rheumatology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Mycobacterium Tuberculosis Infection ... a person with infectious ... and molecular diagnostic ... #management #opportunistic ... #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
: • Dry eyes • ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
vessels (aorta) • Eyes ... /EGPA • RA Diagnosis ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management