7 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Related Acute Lung ... Presents as dyspnea ... Blood products contain ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung ... Presents as dyspnea ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... Fibrin degradation products ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... • Major blood ... dissemination occurs and produces ... change in the lungs ... Fungal #Diagnosis #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Cough • Dyspnea ... genes and gene products ... classification #hematology ... #oncology #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate produced ... diagnose concomitant infection ... Acute Pseudogout: Treatment ... Deposition #Disease #Rheumatology ... #diagnosis #management