111 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... and Medication Targets ... the different pathophysiologic ... #Medication #Targets ... #Drug #Endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - Differential ... Miscellaneous - Bone ... Hyperthyroid, Bony ... Hypercalcemia #Differential ... Algorithm #causes #endocrinology
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... involucrum • Paget ... lytic-blastic phase • Paget ... blade of grass sign ... #Differential #
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Comparison #Table #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
absorption ↑ bone ... Hypophosphatemia: ↑ bone ... Calcium #Phosphorus #pathophysiology ... #endocrinology
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
in subchondral bone ... architecture -> Palpable bony ... contact between bony ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
different types of bone ... involucrum • Paget ... lytic-blastic phase • Paget ... blade of grass sign ... #Differential #
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... easily/weakness, Bone ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Vertebral Body Abnormalities

A sheet of common (and uncommon) vertebral body findings, because a completely “normal” spine
Vertebral Body Abnormalities ... uncommon) vertebral body ... Hyperparathyroidism Paget ... Sclerotic Mets Bone ... Vertebrae #diseases #differential