19 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Dietary Deficiency ... • Small Bowel ... Macrocytosis, Target Cells ... B12 and Folate Deficiency
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... • Improve the symptoms
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... dental fixatives, Treatment ... Haematological: Anaemia ... drkeithsiau #Copper #Deficiency ... #riskfactors #symptoms
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Out Secondary Causes ... or folic acid deficiency ... factor (GCSF) treatments ... • Copper deficiency
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel ... Management Global IBS Symptoms ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... gastroenterology #treatment
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
• Signs and symptoms ... disease • Iron-deficiency ... anemia unresponsive ... to treatment ... without discernable cause
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel ... for diagnosis Treatment ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... IBS #Irritable #Bowel
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
These cells can ... Crises can be precipitated ... of the baseline anaemia ... co-existent G6PD deficiency ... Features #Signs #Symptoms
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... • Common Causes ... to manifest its symptoms ... , alcohol use, symptoms ... Check for IF ab Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... changes, stroke symptoms ... limb ischemia, bowel ... Lysis of tumor cells