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Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... conditions (autoimmune, infectious ... susceptibility, infectious ... CRP, AST+ALT, ferritin ... AOSD: F>M, low ferritin
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... dysfunction, ↑ Ferritin ... • Autoimmune diseases ... Adult-onset Still disease ... , Infection under
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... can mimic common infections ... cell activity • Ferritin ... Treatment: • Infection
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Alopecia: - Infectious ... Capitis - Skin Disease ... Post op, Post infection ... of any comorbid disease ... • Serum iron & ferritin
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... Adult-onset Still disease ... of underlying disease ... SLE], AOSD) • Infection ... dehydrogenase • ↑ Ferritin
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... histoplasmosis #Ferritin
Radiographic appearances of pulmonary disease in HIV-infected patients By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious
appearances of pulmonary disease ... IDFellowCase #ID #Infectious ... Diseases #Infections
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
Differential Diagnosis Ferritin ... > 1000 Ferritin ... hepcidin prevents ferritin ... Infection -16% ... Infection - 46%
IDSA Aspergillosis Treatment • Invasive pulmonary aspergillosis (IPA) • CNS aspergillosis • Cardiac Aspergillus infection •
Cardiac Aspergillus infection ... • Aspergillus infections ... of eye Infectious ... Diseases Fellows
Infectious Diseases Presenting with Rash #InfectiousDisease #Infections #Rashes #Comparison #Table #Differential #Diagnosis
Infectious Diseases ... InfectiousDisease #Infections
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