19 results
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... fluid/Lactated ringers ... #Diagnosis #Management ... #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... diuresis, Bartter's syndrome ... use), Gitelman's syndrome ... #Causes #differential ... #diagnosis #nephrology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... vonWillebrand #Syndrome ... #treatment #hematology ... #differential
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... iniury, Compartment syndrome ... Dialysis for severe hyperkalemia ... #Diagnosis #Management
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
for aggressive treatment ... The longer the seizure ... cause aspiration, hyperkalemia ... #Management #Neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... hydration - Hyperkalemia ... treatment (no calcium ... TLS #diagnosis #management ... #hematology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) hypokalemic ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... life-threatening Differential ... stimulation - Single fiber ... Gravis #diagnosis #management ... #neurology
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... In persistent hypokalemia ... #Management #Treatment ... #nephrology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... death Miller Fisher ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology