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hematology causes algorithm classification high hyperkalemia potassium cold disease extravascular hemolysis hodgkins intravascular lymphoma management oncology platelets testing thrombocytosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
nose, ears, or fingers ... fatigue, pallor, dyspnea ... Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold agglutinins ... #Anemia #Differential ... #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... . primary cold agglutin ... G6PD deficiency) ... Extravascular #Causes #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hematology for workup ... blood loss, Acute hemolysis ... , deficiency anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Cough • Dyspnea ... nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Hyperkalemia - Differential ... Diagnosis Framework ... - Metabolic Acidosis ... - Insulin deficiency ... Crush injury, Hemolysis
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
leukocytosis, in vitro hemolysis ... Acidosis B. ... aldosterone synthase deficiency ... #Hyperkalemia #Differential ... #Diagnosis #High
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