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hematology management neurology abnormal agglutinin color discoloration disease encephalopathy gravis hemolytic monoclonal myasthenia paraproteinemias posterior pres reversible urine
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... nose, ears, or fingers ... Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Thrombosis in vascular beds-renal ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Causes Abnormal Urine Color - Differential Diagnosis Turbid White Urine (Albinuria): • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Diagnosis Turbid ... mirabilis, E. coli ... Intravascular hemolysis ... deficiency, sickle cell anemia ... #Diagnosis #nephrology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
muscles: “myasthenic crises ... life-threatening Differential ... myasthenia Diagnosis ... Myasthenia Crises ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
• Hypertensive crisis ... by 24 hours or longer ... Reversible course Differential ... Seizures: Treat with AEDs ... #neurology
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