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diagnosis hematology hemolytic aiha algorithm causes cold compared comparison disease erythemas extravascular hemolysis intravascular pancytopenia testing workup
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Table Warm AIHA ... hemoglobinuria) • Cold Agglutinin ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... nose, ears, or fingers ... CLL (older) • Autoimmune ... younger pts) Differential ... #hematology #diagnosis
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Inflammatory and Autoimmune ... Diseases: • Systemic ... #Diagnosis #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold agglutinins ... elliptocytosis, autoimmune ... #Differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... . primary cold agglutin ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... multiforme • Acute systemic ... Erythemas #comparison #table ... #differential # ... diagnosis #dermatology
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