27 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... common sites: hip, shoulder ... • Differentiate ... #diagnosis #causes ... #hematology
Perilunate Dislocation
On lateral wrist XR, the capitate ("apple") should sit in the lunate ("tea cup") which
capitate ("apple") should ... tea cup") which should ... dorsally and no longer ... Radiology #XRay #Diagnosis ... #Management #Orthopedics
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Emergencies - Differential ... Diagnosis Framework ... • Dyspnea at rest ... • Chest and shoulder ... #diagnosis #cancer
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
is a skin prick test ... Behcet disease) Differential ... Nonsurgical abdominal pain ... #diagnosis #management ... signs #symptoms #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... -60 minutes or longer ... #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... nose, ears, or fingers ... younger pts) Differential ... chills, flank pain ... test #cold #
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Orthopedic Emergencies ... affected part should ... • Diagnosis: ... - Intense pain ... days, the local pain
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... Diagnosis Framework ... The evaluation should ... II ○ Susac’s syndrome ... #Diagnosis #otology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... • Fever is the main ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... blockers had the best ... #Rheumatology # ... diagnosis #management