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hematology anemia differential product reactions workup agglutinin causes classification cold common cvid disease evaluation hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma macrocytic
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... the peripheral blood ... purpura/hemolytic ... , Hematology 2012 ... , p 193 #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #hematology #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
nose, ears, or fingers ... Diagnosis: • hemolytic ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... #anemia #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... loss, hemolysis ... (BM) ablative disorders
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... hemostasis: - Thrombocytopenia ... Vasculitis - Collagen disorders ... #dermatology #physicalexam
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Febrile Non-Hemolytic ... purpura & severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Hemolysis on labs ... purpura & severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... specifically immune thrombocytopenia ... and autoimmune hemolytic ... and M panel Management ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... Workup: • Full Blood ... marrow biopsy - if blood ... #oncology #management
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