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differential dermatomyositis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune classification common management myopathy myositis pathophysiology pm polymyositis primarycare skin symptoms vasculitides
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
- Bimodal age distribution ... -> Heliotrope Rash ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... mucositis - Rash ... episcleritis as well as inner ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... , mucositis • Rash ... #Rheumatology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
Dermatological Conditions - Distribution ... associated with signs ... ; pruritis #dermatology ... #rash #differential ... #diagnosis #skin
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
DM with generalized ... to have typical DM ... (blue-purple) rash ... #management #rheumatology ... #dermatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... flexors, quadriceps, finger ... elevated < PM and DM
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