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differential hematology monoclonal anemia aplastic autoimmune clinical gammopathy idiopathic iims inflammatory management mgus myopathies myositis paraproteinemias significance
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... late-onset nemaline myopathy ... capillary leak syndrome ... • Schnitzler syndrome ... #hematology #oncology
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
antisynthetase syndrome ... Myopathies #IIMs #diagnosis ... #rheumatology # ... dermatology #Myopathy ... #Rash
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Constitutional Syndromes ... • Peripheral Pancytopenia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... late-onset nemaline myopathy ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... Symptoms: • Gottron rash ... flexors, quadriceps, finger ... #rheumatology #
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