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differential pathophysiology clinical dermatomyositis rheumatology vasculitis autoimmune crest diffuse lesions mechanics myelopathy myopathy myositis pm polymyositis pustular rash scleroderma secondary
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
) • Hand paresthesias ... , fine finger dexterity ... #Myelopathy #diagnosis ... #signs #symptoms ... #msk
CREST Syndrome: Pathogenesis and Clinical Findings CALCINOSIS (BB-sized, hard nodules in fingers) RAYNAUD'S Phenomenon ESOPHAGEAL DYSMOTILITY SCLERODACTYLY (thickening and tightening
hard nodules in fingers ... tightening of skin ... TELANGIECTASIA (In face, hands ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
nodules under skin ... ) - Finger/hand ... and bushy - Finger ... pathophysiology #signs ... #symptoms #diagnosis
Mechanic’s Hands in Dermatomyositis Finally, mechanic’s hands which are common to Anti-synthetase syndrome and another type of
Anti-synthetase syndrome ... another type of DM ... of the distal finger ... Dermatomyositis #Dermatology ... #Clinical #Photo
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... dorsum of the hands ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Irregular pustules on hands ... Burrows between fingers ... SAPHO syndrome ( ... #Dermatology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... #Clinical #Photo ... #Dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... occasional oligoclonal bands
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... ) • Shawl sign ... flexors, quadriceps, finger ... elevated < PM and DM ... • Mechanic's hands
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