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diagnosis hematology oncology arthritis workup causes cll disease lymphocytic msk pain thrombocytosis vasculitis agglutinin algorithm approach autoimmune classification cold hemeonc
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... hemorrhage) • Chronic ... inflammatory disorders ... myeloid leukemia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Myelogenous Leukemia ... : • Acute or Chronic ... • Rheumatic disorders ... Iron deficiency anemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... onset of symptoms ... bone pain, fever, joint ... - infiltrates (anemia ... #Hematology #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... in adults • Disorder ... of anemia or thrombocytopenia ... marrow failure with anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... lymphoproliferative disorders ... • Neutropenia, anemia ... #CLL #Chronic
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... Mechanical/degenerative disorders ... constitutional symptoms ... - Autoimmune Rheumatologic ... #pain #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
nose, ears, or fingers ... of anemia include ... • hemolytic anemia ... younger pts) Differential ... #hematology #diagnosis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... -60 minutes or longer ... : • Acute or chronic ... #Pain #MSK #rheumatology ... approach #workup #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Marrow Failure • Chronic ... Myelogenous Leukemia ... blood count with differential
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